Go straight to H7N9 avian influenza articles

The A(H7N9) virus

Influenza A H7 viruses are a group of influenza viruses that normally circulate among birds. The influenza A(H7N9) virus is one subgroup among the larger group of H7 viruses. Although some H7 viruses (H7N2, H7N3 and H7N7) have occasionally been found to infect humans, no human infections with H7N9 viruses have been reported until March 2013, when three urban residents of Shanghai or Anhui, China, presented with rapidly progressing lower respiratory tract infections and were found to be infected with a novel reassortant avian-origin influenza A (H7N9) virus.

Developing a vaccine

There is currently no vaccine for the prevention of avian influenza A(H7N9) infections although at least four biopharmaceutical companies have candidates that are being tested in animal and human trials. (Wu YL, Shen L-W, Ding Y-P. Preliminary success in the characterization and management of a sudden breakout of a novel H7N9 influenza A virus. International Journal of Biological Sciences, 2014, volume 10, number 1, pages 109-118. Full text : Bart SA. et al. A Cell Culture–Derived MF59-Adjuvanted Pandemic A/H7N9 Vaccine Is Immunogenic in Adults. Sci Transl Med 30 April 2014: Vol. 6, Issue 234, p. 234ra55
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****General Resources****

 

WHO Avian influenza A(H7N9) virus

This webpage lists up-to-date information on the developing H7N9 situation. It includes updates on human infection caused by the avian influenza A(H7N9) virus, numbers of confirmed human cases reported to the WHO, technical guidance and frequently asked questions.
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Avian Influenza A(H7N9) Response:An Investment in Public Health Preparedness

WHO 2013
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Hong Kong Centre for Health Protection (CHP)

Avian influenza

Weekly avian influenza report

Chinese Center for Disease Control and Prevention

H7N9

Weekly updates

Frequently asked questions

Research highlights

Dr Ian M Mackay Avian influenza A virus H7N9...

Virology Down Under, University of Queensland, Australia
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H7N9 Summary

Influenza Specialist Group, Australia
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****Recent Journal Articles****

 

Dong L. et al. A Combination of Serological Assays to Detect Human Antibodies to the Avian Influenza A H7N9 Virus. (China) PLoS One. 2014 Apr 22;9(4):e95612.
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Gao GF. Influenza and the live poultry trade. Science. 2014 Apr 18;344(6181):235.

Gao R. et al. Ultrastructural characterization of avian influenza A (H7N9) virus infecting humans in China. Virol Sin. 2014 Apr;29(2):119-22.

Kang X. et al. Detection of Avian influenza A/H7N9/2013 virus by Real-Time Reverse Transcription-Polymerase Chain Reaction. J Virol Methods. 2014 May 28. pii: S0166-0934(14)00128-1.
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Khazeni N. et al. Health and Economic Benefits of Early Vaccination and Nonpharmaceutical Interventions for a Human Influenza A (H7N9) Pandemic: A Modeling Study. Ann Intern Med. 2014 May 20;160(10):684-94.
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Krammer F. et al. Divergent H7 Immunogens Offer Protection from H7N9 Virus Challenge. J Virol. 2014 Apr;88(8):3976-85.
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Liu C. et al. Extracorporeal membrane oxygenation as rescue therapy for H7N9 influenza-associated acute respiratory distress syndrome. Chin Med J 2014 May;127(9):1798.
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Lu J. et al.
Genetic changes of reemerged influenza A(H7N9) viruses, China. Emerg Infect Dis 2014 (published online May 23)
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Pantin-Jackwood MJ. et al. Role of poultry in the spread of novel H7N9 influenza virus in China. J Virol. 2014 May;88(10):5381-90.
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Qiao JG. et al. Management of the First Confirmed Case of Avian Influenza A H7N9. Respir Care. 2014 Apr;59(4):e43-6.
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Shen Y, Lu H. Human infection with avian influenza A(H7N9) virus in Shanghai: current status and future trends. Chin Med J. 2014 May;127(10):1973-6.
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Su S. et al. Virological and Epidemiological Evidence of Avian Influenza Virus Infections Among Feral Dogs in Live Poultry Markets, China: A Threat to Human Health? Clin Infect Dis. 2014 Apr 4. [Epub ahead of print]
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Sun J. et al. Comparison of Characteristics between Patients with H7N9 Living in Rural and Urban Areas of Zhejiang Province, China: A Preliminary Report. PLoS One. 2014 Apr 7;9(4):e93775.
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To KK1, Chan JF, Yuen KY. Viral lung infections: epidemiology, virology, clinical features, and management of avian influenza A(H7N9). Curr Opin Pulm Med. 2014 May;20(3):225-32.
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Wang L. et al. Human exposure to live poultry and psychological and behavioral responses to influenza A(H7N9), China. Emerg Infect Dis 2014 (published online May 28)
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Wang W. et al.
PCR for detection of oseltamivir resistance mutation in influenza A(H7N9) virus. Emerg Infect Dis. 2014 May;20(5):847-9.
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Wang W. et al. Serologic assay for avian-origin influenza A (H7N9) virus in adults of Shanghai, Guangzhou and Yunnan, China. J Clin Virol 2014 (published online Apr 13)
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Wang X. et al. Seroprevalence to avian influenza A(H7N9) virus among poultry workers and the general population in southern China: a longitudinal study. Clin Infect Dis 2014 (published online May 27)
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Wu P. et al.
Responses to threat of influenza A(H7N9) and support for live poultry markets, Hong Kong, 2013. Emerg Infect Dis. 2014 May;20(5):882-6.
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Xie T. et al. C
orrelation between reported human infection with avian influenza A H7N9 virus and cyber user awareness: what can we learn from digital epidemiology? Int J Infect Dis. 2014 May;22:1-3.
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Zhang J. et al. Determination of original infection source of H7N9 avian influenza by dynamical model. Sci Rep. 2014 May 2;4:4846.
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Zhang J, Zhao Y, Chen Y.
Laboratory findings in patients with avian-origin influenza A (H7N9) virus infections. J Med Virol. 2014 May;86(5):895-8.
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Zhang Y. et al.
Isolation and characterization of H7N9 avian influenza A virus from humans with respiratory diseases in Zhejiang, China. Virus Res. 2014 May 24. pii: S0168-1702(14)00183-X.
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Zhu G, Peterson AT. Potential Geographic Distribution of the Novel Avian-Origin Influenza A (H7N9) Virus. PLoS One. 2014 Apr 1;9(4):e93390.
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H7N9 Journal Articles


H7N9 Avian Influenza Bibliography April 2013 - April 2014